Contact details

T: +44 (0) 1225 810361
F: +44 (0) 1225 810153
Medical Wire & Equipment
SN13 9RT
Registered in England & Wales Company No. 571118
VAT No. GB 137 6960 39

Sigma SP™*

Sputum is an important biological material for the investigation of respiratory disease, but is notoriously difficult to work with. Various reagents have been used over the years to liquefy sputum specimens to make them suitable for inoculation onto agar. Some of these reagents must be prepared in caustic solutions, and can be unsafe and unpleasant to handle, with limited stability. They are normally kept lyophilised and prepared when required.

Many microbiology laboratories now use automated processing platforms for the inoculation of agar plates, but the current methods of preparation of sputum specimens are not well suited for this technology. Specimens are loaded in large numbers onto the equipment, but may wait for several hours before being processed. Commonly used reagents such as dithiothreitol are detrimental to the survival of important respiratory pathogens such as Haemophilus influenzae. MWE’s new Sigma SP™ resolves all of these issues. Sigma SP™ contains a novel reagent which is not only a more powerful mucolytic, but comes in a simple, ready to use liquid format. When the sputum is added, the Sigma SP™ tube is loaded directly onto the automated platforms. It is not directly harmful to any of the target bacteria, so specimens can be safely left in the queue for several hours. The solution has a neutral pH, and can be safely stored prior to use at ambient temperature for many months.

To use simply add 1ml of sputum directly to the Sigma SP™ vial, recap, vortex and allow to stand for about 15 minutes before processing.

Initial studies show that Sigma SP™ liquid does not interfere with molecular diagnostic test systems.

Fast simple preparation of sputum for automated and manual inoculation.

• Ready to use

• Neutral pH

• Powerful mucolytic

• Effective recovery of respiratory bacteria

• Use directly with automated processing

• Convenient for manual processing

• Ambient storage



For more information please click here.


MWSP_Sigma SP Tube amp Background